SmithRx

What is SmithRx?

SmithRx is a pharmacy benefit manager (PBM) built to fix what its founders saw as broken about traditional PBMs. Self-insured employers use SmithRx to manage prescription-drug benefits for their employees, and the company runs a transparent, pass-through model: rather than profiting from a spread between what it pays and what it charges, SmithRx says it passes through drug costs and rebates to clients and operates independently from insurance companies and pharmacies, so its incentives align with the employers and members it serves rather than with drug manufacturers or middlemen. It backs this with drug-cost, rebate, and service-level guarantees, delivered through a single, modern technology platform paired with concierge-level service, and modern cost-savings programs designed to connect members to the lowest-cost version of their medication. SmithRx was founded in 2016 by Jake Frenz, who is CEO, and is headquartered in San Francisco, California. It employs roughly 550 people and has raised about $89 million in total funding, including a $60 million Series C led by Venrock (an earlier $20 million Series B was also led by Venrock, with Founders Fund participating). SmithRx was recognized on Modern Healthcare's Best in Business list for 2025, its second consecutive year on the list.

Mission & values

Fix the broken economics of pharmacy benefits with a transparent, pass-through model that aligns SmithRx's incentives with its clients and their members.

Qualifications

SmithRx hires across the functions of a healthcare technology and pharmacy-benefits company. On the technical side: software engineering (backend, frontend, full-stack, and data), data science and analytics (pricing, rebates, and clinical cost programs depend on strong data work), and product management and design. Because it operates a real PBM, it also hires clinical and pharmacy roles (pharmacists, clinical program staff), pharmacy operations, and account management/client success (its "concierge-level service" promise), plus implementation, sales, actuarial/underwriting, compliance, finance, and people. Application flow lives at smithrx.com/careers. The company is headquartered in San Francisco and hires across the US; some roles are remote or hybrid and others are tied to an office, and roles require US work authorization. Healthcare, PBM, pharmacy, or health-benefits experience is a strong signal for clinical and operations roles; strong data and engineering skills matter across the technical side. Check each posting for location and remote eligibility.

Leadership

Hiring process

1. 1

   Apply at smithrx.com careers

   Browse engineering, data, clinical/pharmacy, account management, implementation, sales, and corporate roles and submit through the SmithRx careers site.

2. 2

   Recruiter screen

   Confirms role fit, level, US work authorization, remote/hybrid vs office expectations, and pay.

   About 7 days

3. 3

   Technical or role-specific interview

   Engineering/data: coding and system design. Clinical/pharmacy: a benefits or clinical-program scenario. Account management: a client scenario.

   About 10 days

4. 4

   Team interviews

   Cross-functional interviews with the team on depth, judgment, and fit for a mission-driven healthtech company.

   About 10 days

5. 5

   Offer

   Offer with base plus equity where applicable, aligned to role and location.

   About 7 days

Funding

Awards & recognition

• Named to Modern Healthcare's Best in Business list for the second consecutive year · 2025

  Modern Healthcare

• Raised a $60M Series C led by Venrock · 2025

  SmithRx

Company information

• Industry: HealthTech / Pharmacy Benefit Management (PBM)
• Location: San Francisco, CA, USA (US; some remote/hybrid)
• Founded: 2016
• Employees: 550
• Website: smithrx.com ↗
• LinkedIn: Company page ↗

Frequently asked questions