Ambience Healthcare
AI scribe & clinical workflow platform — $1.25B unicorn backed by a16z, Oak HC/FT, Kleiner Perkins, and the OpenAI Startup Fund.
What is Ambience Healthcare?
Ambience Healthcare is a San Francisco-based AI clinical documentation platform founded in 2020 by Nikhil Buduma and Mike Ng. The platform sits with clinicians in real time across outpatient, emergency, and inpatient settings — listening to the visit, generating coding-aware documentation, surfacing chart context, and flagging conditions for the differential. It supports 100+ medical specialties and is used by top health systems across North America. Ambience raised a $243M Series C (July 2025) co-led by a16z and Oak HC/FT, valuing the company at over $1.25B (up from ~$300M at its $70M Series B in Feb 2024). Total raised: ~$373M. Backers also include the OpenAI Startup Fund, Kleiner Perkins, Optum Ventures, Georgian, and Frist Cressey Ventures. In September 2025 co-founder Nikhil Buduma stepped up from Chief Scientist to CEO; Mike Ng shifted to President & Chairman.
Mission & values
Free clinicians from the administrative burden of the EHR — let them spend their time on patients while AI handles real-time, coding-aware documentation.
Qualifications
Ambience hires across machine learning research, applied AI engineering, full-stack/platform engineering, infrastructure, product, clinical (RN/MD informaticists), design, sales (health systems and provider groups), and customer success. Many engineering and research roles are remote-friendly. Compensation tracks high-end SF AI-startup bands with meaningful equity and clinical-mission framing. Apply at https://www.ambiencehealthcare.com/careers.
Leadership
Nikhil Buduma
Co-Founder & CEO
Co-founded Ambience in 2020 as Chief Scientist; stepped into the CEO role in September 2025.
Mike Ng
Co-Founder, President & Chairman
Co-founded Ambience in 2020 and served as CEO until September 2025, when he shifted into a full-time executive role as President and Chairman.
Hiring process
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1
Apply at ambiencehealthcare.com/careers
Submit application for an open role.
About 1 day
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2
Recruiter screen
Initial conversation about role and background.
About 5 days
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3
Hiring manager interview
Discussion of role specifics; clinical roles may include peer-MD/RN screen.
About 5 days
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4
Technical / clinical loop
Multi-round interviews — for engineering, expect coding + system design + ML research depth.
About 10 days
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5
Offer
Compensation, equity, and onboarding discussion.
About 3 days
Funding
Awards & recognition
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$1.25B+ valuation at $243M Series C · 2025
Bloomberg / Becker's Hospital Review
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Backed by OpenAI Startup Fund + a16z + Kleiner Perkins
Ambience Healthcare
Company information
- Industry: Healthcare AI / Clinical Documentation
- Location: San Francisco, CA, USA
- Founded: 2020
- Company size: 201-1000
- Website: www.ambiencehealthcare.com ↗
- LinkedIn: Company page ↗
- X / Twitter: Profile ↗