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Principal Clinical Scientist

Alignerr

AI Expert - Clinical & Medical Contractor
Remote (Global) $40 – $80/hr June 22, 2026

Job description

Principal Clinical Scientist (AI Training)

About the Role

What if your career spent designing rigorous clinical trials and interpreting regulatory-grade data could directly influence how AI reasons about medicine? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the development of cutting-edge AI systems — ensuring the models shaping the future of biomedical research are built on a foundation of scientific rigor.

This is a fully remote, flexible contract role. You won't be running trials or filing submissions — you'll be doing something arguably more consequential: teaching AI to think like a seasoned clinical scientist.

  • Organization: Alignerr
  • Type: Hourly Contract
  • Location: Remote
  • Commitment: 10–40 hours/week

What You'll Do

  • Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
  • Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
  • Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
  • Identify gaps, errors, and weaknesses in how AI models reason about clinical evidence — and provide expert feedback to correct them
  • Help define what "good" looks like when AI tackles clinical trial data, outcomes, and methodology
  • Work independently and asynchronously on task-based assignments — on your own schedule

Who You Are

  • Senior clinical scientist with deep, hands-on experience designing clinical trial protocols for regulatory submission
  • Expert interpreter of clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
  • Strong grounding in clinical research methodology, biostatistics, or translational science
  • Precise, rigorous thinker who can spot flawed reasoning or incomplete analysis quickly
  • Clear written communicator who can document feedback in structured, actionable formats
  • Self-motivated and reliable when working independently without direct supervision

Nice to Have

  • Prior experience with data annotation, data quality evaluation, or AI training workflows
  • Background in regulatory affairs, pharmacovigilance, or clinical operations
  • Familiarity with AI tools or model evaluation platforms as an end user
  • Experience in oncology, rare disease, or other complex therapeutic areas

Why Join Us

  • Work on frontier AI systems alongside leading AI research labs — at the cutting edge of clinical and biomedical AI
  • Fully remote and flexible — work when and where it suits you
  • Freelance autonomy with the structure of meaningful, expert-level work
  • Make a direct, lasting impact on how AI understands and evaluates real-world clinical evidence
  • Influence the standards that define how AI models approach regulatory science
  • Potential for ongoing work and contract extension as new projects launch
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